The most modern format of medicine of the Digital World
Treatment combo Sessions of Modern Medicine in Digital format - L
The frequencies used in these sessions are based upon Rife sets for resonant therapy devices masked in Algorithmic piano music.
More information regarding the items in the list is given below the list.
List of Treatment combo Sessions of Modern Medicine in Digital format for problems/products available at us for just Rs. 1,000/- for any 5 sessions from any one or multiple Treatment combo Sessions for 30 doses per session (2 times a day for 15 days) in max 15 days.
1) Labyrinth Diseases
2) Lacrimal Apparatus Diseases
3) Lacrimal Duct Obstruction
4) Lactation Disorders
5) Lactobacillus Acidophilus
6) Lactose Intolerance
7) Lambert-Eaton Myasthenic Syndrome
8) Laryngeal Diseases
9) Laryngeal Stenosis
10) Laryngitis
11) Laryngomalacia
12) Lassa Fever
13) Lateral Bulbar Syndrome
14) Lateral Sclerosis
15) Leaky Gut Syndrome
16) Left Ventricular Hypertrophy
17) Leg Ulcer
18) Leishmaniasis
19) Lentiginosis Perioral
20) Lentigo
21) Leprosy
22) Leptospirosis
23) Leucine Metabolism Disorders
24) Leukemia
25) Leukoencephalitis Subacute Sclerosing
26) Leukopenia
27) Lichen Planus
28) Lichen Sclerosus et Atrophicus
29) Light Sensitivity
30) Lipodystrophy
31) Lipodystrophy Intestinal
32) Lipoma
33) Lipomatosis
34) Livedo Reticularis Systemic
35) Liver Diseases
36) Loiasis
37) Lordosis
38) Ludwig Angina
39) Lumbago
40) Lung Abscess
41) Lung Collapse
42) Lung Diseases
43) Lung Diseases-Interstitial
44) Lymphadenitis
45) Lymphangioma
46) Lymphatic Diseases
47) Lymphedema
48) Lymphogranuloma Venereum
49) Lymphoproliferative Disorders
50) Lysosomal Storage Diseases
* Lacrimal or nasolacrimal duct obstruction (NLDO) is the obstruction of
nasolacrimal duct and may be either congenital or acquired. Obstruction of the
nasolacrimal duct leads to the excess overflow of tears called epiphora.
Involutional stenosis is probably the most common cause of NLD obstruction in
older persons. It affects women twice as frequently as men. Dacryoliths or cast
formation, within the lacrimal sac can also produce obstruction of the NLD.
Sinus disease often occurs in conjunction with, and in other instances may
contribute to the development of NLD obstruction. Naso-orbital fractures may
involve the NLD. Granulomatous disease, including sarcoidosis, granulomatosis
with polyangiitis,and midline granuloma, may also lead to NLD obstruction. As
with similar cases of canalicular obstruction, dislodged punctal and canalicular
plugs can migrate to and occlude the NLD. Neoplasm should be considered in any
patient presenting with NLD obstruction.In patients with an atypical
presentation, including younger age and male gender,further workup is
appropriate. Bloody punctal discharge or lacrimal sac distension above the
medial canthal tendon is also highly suggestive of neoplasm. Congenital
nasolacrimal duct obstruction, or dacryostenosis, occurs when the lacrimal duct
has failed to open at the time of birth, most often due to an imperforate
membrane at the valve of Hasner. Around 6% of infants have CLDO, usually
experiencing a persistent watery eye even when not crying. If a secondary
infection occurs (Dacryocystitis), purulent (yellow / green) discharge may be
present.
* Lactation disorders, disturbances of milk secretion in either sex, not
necessarily related to pregnancy.
* Lactose intolerance is the inability of adults and children to digest lactose,
a sugar found in milk and to a lesser extent dairy products, causing side
effects. It is due to a lactase deficiency, or hypolactasia. Lactose intolerant
individuals have insufficient levels of lactase, an enzyme that catalyzes the
hydrolysis of lactose into glucose and galactose, in their digestive system. In
most cases, this causes symptoms which may include abdominal bloating and
cramps, flatulence, diarrhea, nausea, rumbling stomach, or vomiting after
consuming significant amounts of lactose. Most mammals normally cease to produce
lactase (lactase nonpersistence), becoming lactose intolerant, after weaning,
but some human populations have developed lactase persistence, in which lactase
production continues into adulthood.
* Lambert-Eaton myasthenic syndrome, neuromuscular disorder which causes
progressive muscle weakness, usually first noticed in the upper legs and upper
arms.
* Laryngeal diseases may be caused by vocal abuse, misuse, and overuse: Several
disorders of the larynx can be caused by strain or injury to the vocal cords
through excessive talking, throat clearing, coughing, smoking, screaming,
singing, or speaking too loudly or too low. Eventually, frequent vocal abuse and
misuse can cause permanent changes in vocal function and possibly the loss of
voice. Almost every disorder of the larynx may result in more than one symptom,
and there is no single symptom associated with a specific disorder of the
larynx. For example, hoarseness, limitations in pitch and loudness, shortness of
breath or increased vocal effort may be a sign of any number of disorders of the
larynx.
* Laryngomalacia (literally, "soft larynx") is the most common cause of stridor
in infancy, in which the soft, immature cartilage of the upper larynx collapses
inward during inhalation, causing airway obstruction. It can also be seen in
older patients, especially those with neuromuscular conditions resulting in
weakness of the muscles of the throat. However, the infantile form is much more
common. Laryngomalacia results in partial airway obstruction, most commonly
causing a characteristic high-pitched squeaking noise on inhalation (inspiratory
stridor). Some infants have feeding difficulties related to this problem.
Rarely, children will have significant life-threatening airway obstruction. The
vast majority, however, will only have stridor without other more serious
symptoms such as dyspnea (difficulty breathing).
* Laryngotracheal stenosis refers to abnormal narrowing of the central air
passageways. This can occur at the level of the larynx, trachea, carina or main
bronchi. In a small number of patients narrowing may be present in more than one
anatomical location. The most common symptom of laryngotracheal stenosis is
gradually-worsening breathlessness (dyspnea) particularly when undertaking
physical activities (exertional dyspnea). The patient may also experience added
respiratory sounds which in the more severe cases can be identified as stridor
but in many cases can be readily mistaken for wheeze.
* Lassa fever is an acute viral illness that occurs in west Africa. The virus, a
member of the virus family Arenaviridae, is a single-stranded RNA virus and is
zoonotic, or animal-borne. Transmission of Lassa virus to humans occurs most
commonly through ingestion or inhalation. Mastomys rodents shed the virus in
urine and droppings and direct contact with these materials, through touching
soiled objects, eating contaminated food, or exposure to open cuts or sores, can
lead to infection. Mild symptoms include slight fever, general malaise and
weakness, and headache. In 20% of infected individuals, however, disease may
progress to more serious symptoms including hemorrhaging (in gums, eyes, or
nose, as examples), respiratory distress, repeated vomiting, facial swelling,
pain in the chest, back, and abdomen, and shock. Neurological problems have also
been described, including hearing loss, tremors, and encephalitis. Death may
occur within two weeks after symptom onset due to multi-organ failure.
* Lateral bulbar syndrome is a disorder in which the patient has a constellation
of neurologic symptoms due to injury to the lateral part of the medulla in the
brain, resulting in tissue ischemia and necrosis. his syndrome is characterized
by sensory deficits affecting the trunk (torso) and extremities on the opposite
side of the infarction and sensory deficits affecting the face and cranial
nerves on the same side with the infarct. Specifically, there is a loss of pain
and temperature sensation on the contralateral (opposite) side of the body and
ipsilateral (same) side of the face. Affected persons have difficulty in
swallowing (dysphagia) resulting from involvement of the nucleus ambiguus, as
well as slurred speech (dysarthria) and disordered vocal quality (dysphonia) .
Damage to the spinal trigeminal nucleus causes absence of pain on the
ipsilateral side of the face, as well as an absent corneal reflex. Nystagmus and
vertigo may result in falling, caused from involvement of the region of Deiters'
nucleus and other vestibular nuclei. Onset is usually acute with severe vertigo.
* Leaky gut syndrome is a little known but very common disorder that refers to
an irritated and inflamed small intestine. This irritation or inflammation
results in foreign substances being absorbed into the bloodstream thus causing
symptoms and other health problems.
* Left ventricular hypertrophy (LVH) is thickening of the heart muscle of the
left ventricle of the heart, that is, left-sided ventricular hypertrophy. While
ventricular hypertrophy occurs naturally as a reaction to aerobic exercise and
strength training, it is most frequently referred to as a pathological reaction
to cardiovascular disease, or high blood pressure. It is one aspect of
ventricular remodeling. While LVH itself is not a disease, it is usually a
marker for disease involving the heart. Disease processes that can cause LVH
include any disease that increases the afterload that the heart has to contract
against, and some primary diseases of the muscle of the heart. Causes of
increased afterload that can cause LVH include aortic stenosis, aortic
insufficiency and hypertension. Primary disease of the muscle of the heart that
cause LVH are known as hypertrophic cardiomyopathies, which can lead into heart
failure. Long-standing mitral insufficiency also leads to LVH as a compensatory
mechanism. The enlargement is not permanent in all cases, and in some cases the
growth can regress with the reduction of blood pressure. LVH may be a factor in
determining treatment or diagnosis for other conditions. For example, LVH causes
a patient to have an irregular ECG.
* Leg ulcer refers to full thickness skin loss on the leg or foot due to any
cause. Leg ulcers occur in association with a range of disease processes, most
commonly with blood circulation diseases.
* Leishmaniasis, also spelled leishmaniosis, is a disease caused by protozoan
parasites of the genus Leishmania and spread by the bite of certain types of
sandflies. The disease can present in three main ways: cutaneous, mucocutaneous,
or visceral leishmaniasis. The cutaneous form presents with skin ulcers, while
the mucocutaneous form presents with ulcers of the skin, mouth, and nose, and
the visceral form starts with skin ulcers and then later presents with fever,
low red blood cells, and enlarged spleen and liver.
* Lentiginosis perioral, also Peutz-Jeghers syndrome is characterized by the
development of noncancerous growths called hamartomatous polyps in the
gastrointestinal tract (particularly the stomach and intestines) and a greatly
increased risk of developing certain types of cancer. Children with
Peutz-Jeghers syndrome often develop small, dark-colored spots on the lips,
around and inside the mouth, near the eyes and nostrils, and around the anus.
These spots may also occur on the hands and feet. They appear during childhood
and often fade as the person gets older. In addition, most people with
Peutz-Jeghers syndrome develop multiple polyps in the stomach and intestines
during childhood or adolescence. Polyps can cause health problems such as
recurrent bowel obstructions, chronic bleeding, and abdominal pain. People with
Peutz-Jeghers syndrome have a high risk of developing cancer during their
lifetimes. Cancers of the gastrointestinal tract, pancreas, cervix, ovary, and
breast are among the most commonly reported tumors.
* Lentigo, pigmented spots on the skin.
* Leprosy is primarily a granulomatous disease of the peripheral nerves and
mucosa of the upper respiratory tract; skin lesions (light or dark patches) are
the primary external sign. If untreated, leprosy can progress and cause
permanent damage to the skin, nerves, limbs, and eyes. Secondary infections, in
turn, can result in tissue loss causing fingers and toes to become shortened and
deformed, as cartilage is absorbed into the body.
* Leptospirosis is an infection caused by corkscrew-shaped bacteria called
Leptospira. Signs and symptoms can range from none to mild such as headaches,
muscle pains, and fevers; to severe with bleeding from the lungs or meningitis.
If the infection causes the person to turn yellow, have kidney failure and
bleeding, it is then known as Weil's disease. If it causes lots of bleeding from
the lungs it is known as severe pulmonary hemorrhage syndrome. Leptospirosis is
transmitted by the urine of an infected animal and is contagious as long as the
urine is still moist. Although Leptospira has been detected in reptiles and
birds, only mammals are able to transmit the bacterium to humans and other
animals.
* Leucine metabolism disorders. Leucine is an essential amino acid utilized in
the liver, adipose tissue and muscle tissue.
* Leukemia is a group of cancers that usually begin in the bone marrow and
result in high numbers of abnormal white blood cells. These white blood cells
are not fully developed and are called blasts or leukemia cells. Symptoms may
include bleeding and bruising problems, feeling tired, fever, and an increased
risk of infections. These symptoms occur due to a lack of normal blood cells.
* Leukoencephalitis subacute sclerosing or subacute sclerosing panencephalitis
(SSPE) is a progressive neurological disorder characterized by inflammation of
the brain (encephalitis). The disease may develop due to reactivation of the
measles virus or an inappropriate immune response to the measles virus. SSPE
usually develops 2 to 10 years after the original viral attack. Initial symptoms
may include memory loss, irritability, seizures, involuntary muscle movements,
and/or behavioral changes, leading to neurological deterioration.
* Leukopenia, a decrease in the number of white blood cells found in the blood.
It increases the risk of an infection.
* Lichen planus, condition that forms an itchy rash on the skin or in the mouth.
* Lichen sclerosus et atrophicus (LSetA) or lichen sclerosus (LS), is a disease
of unknown cause that results in white patches on the skin, which may cause
scarring on and around genital or sometimes other skin. There is a bimodal age
distribution in the incidence of LS. It occurs in females with an average age of
diagnosis of 7.6 years in girls and 60 years old in women. The average age of
diagnosis in boys is 9–11 years old. Several risk factors have been proposed,
including autoimmune diseases, infections and genetic predisposition. There is
evidence that LS can be associated with thyroid disease. Women are more commonly
affected than men (10 to 1 ratio), particularly around and after menopause, but
younger women or girls may also develop the disease. The condition most commonly
occurs on the vulva and around the anus with ivory-white elevations that may be
flat and glistening. There may be marked itching or the condition may be without
any symptoms. There may also be thinning and shrinkage of the genital area that
may make coitus, urination, and defecation painful. In males, the disease may
take the form of whitish thickening of the foreskin, which cannot be retracted
easily (phimosis). In contrast to women, there is no perianal involvement. In
men, this genital involvement has traditionally been known as balanitis xerotica
obliterans (BXO). Only 6% of LS are isolated extragenital lesions. On the
non-genital skin, the disease may manifest as porcelain-white spots with small
visible plugs inside the orifices of hair follicles or sweat glands on the
surface. Thinning of the skin may also occur.
* Light sensitivity, notable or increased reactivity to light.
* Lipodystrophy intestinal, or Whipple's disease, is a rare systemic infectious
disease caused by the bacterium Tropheryma whipplei. Whipple's disease primarily
causes malabsorption but may affect any part of the body including the heart,
brain, joints, skin, lungs and the eyes.Whipple’s disease interferes with normal
digestion by impairing the breakdown of foods, such as fats and carbohydrates,
and hampering the body’s ability to absorb nutrients. Symptoms tend to develop
slowly over a period of many years in most people with this disease. In some
cases, some symptoms, such as joint pain and weight loss, develop years before
the gastrointestinal symptoms. Gastrointestinal signs and symptoms are common in
Whipple’s disease and may include: Diarrhea, Abdominal cramping and pain, which
may worsen after meals, Weight loss, associated with the malabsorption of
nutrients. Other frequent signs and symptoms associated with Whipple’s disease
include: Inflamed joints, particularly your ankles, knees and wrists, Fatigue,
Weakness, Anemia. In some cases, signs and symptoms of Whipple’s disease may
include: Fever, Cough, Enlarged lymph nodes, Skin darkening (hyperpigmentation)
in areas exposed to the sun and in scars, Chest pain, Enlarged spleen.
Neurological signs and symptoms may include: Difficulty walking, Visual
impairment, including lack of control of eye movements, Seizures, Confusion,
Memory loss. The presentation can be highly variable and approximately 15% of
patients do not have the classic signs and symptoms. Whipple's disease is
significantly more common in men, with 87% of the patients being male.
* Lipodystrophy, irregularities in the lipids -fat absorption process.
* Lipoma is a very slow growing, fatty lump normally found situated between the
skin and the muscle layer underneath the skin. Most often a lipoma is very
simple to identify since it will easily move if there is any pressure on it.
When touched it is very doughy and normally not tender. There may be more than
one. They can develop at any age but most often occur during mid life. A lipoma
is not a cancer and is typically not dangerous. Lipomas are usually found on
back, neck, arms as well as shoulder, but they can develop on any other part of
the body. Additionally, men are most likely to develop multiple lipomas than
woman, although either sex is more equally likely to have single developments.
Often, the most troublesome symptom is the location or the increase in size
which makes the lipoma obviously noticeable by others.
* Lipomatosis, uneven distribution of lipids or fat deposits in the body.
* Livedo reticularis is a common skin finding consisting of a mottled
reticulated vascular pattern that appears as a lace-like purplish discoloration
of the skin. The discoloration is caused by swelling of the venules owing to
obstruction of capillaries by small blood clots. The blood clots in the small
blood vessels can be a secondary effect of a condition that increases a person's
risk of forming blood clots, including a wide array of pathological and
nonpathological conditions . Examples include hyperlipidemia, microvascular
hematological or anemia states, nutritional deficiencies, hyper- and autoimmune
diseases, and drugs/toxins. The condition may be normal or related to more
severe underlying pathology. Its differential diagnosis is broadly divided into
possible blood diseases, autoimmune (rheumatologic) diseases, cardiovascular
diseases, cancers, and endocrine disorders. It may be aggravated by exposure to
cold, and occurs most often in the lower extremities.
* Loiasis is caused by the Loa loa, a thread-like worm that lives under the skin
in the subcutaneous fat. Because it is often spotted migrating in the eye, it is
known as the eye worm. Loiasis is endemic to 11 countries and 12 million
Africans are infected. Loiasis is carried by day-biting deer and mango flies
(Chrysops silacea and Chrysops dimidiata). Loiasis can be asymptomatic. Native
people are more likely to have symptoms than tourists. Adult worms (both living
and dead) and their metabolic byproducts (waste) can cause localized
subcutaneous itching and allergic reactions. The inflammation may cause red skin
eruptions and swelling in the deeper layers of the skin which can last many
weeks. Migrating adults can cause instant pain, when moving in sensitive areas,
for example, across the surface of the eye. Loiasis is often the cause of
eosinophilia (large quantities of eosinophil granulocytes, white cells, that use
antigens and special proteins to fight against foreign organisms such as
parasites.). Other symptoms that may occur: arthritis (joint pain), colonic
lesion (damaged large intestine), inflammation, swelling and accumulation of
fluid in testicles, lymphadenitis (infection of the lymph glands), membranous
glomerulonephritis (kidney disease), peripheral neuropathy (damaged peripheral
nervous system), retinopathy (damaged retina (thin layer on the back wall of the
eye)).
* Lordosis, abnormal forward curvature of the spine in the lumbar region,
resulting in a swaybacked posture.
* Ludwig's angina is a serious, potentially life-threatening cellulitis, or
connective tissue infection, of the floor of the mouth, usually occurring in
adults with concomitant dental infections and if left untreated, may obstruct
the airways, necessitating tracheostomy. Dental infections account for
approximately 80% of cases of Ludwig's angina. Mixed infections, due to both
aerobes and anaerobes, are of the cellulitis associated with Ludwig's angina.
Typically, these include alpha-hemolytic streptococci, staphylococci and
bacteroides groups. The route of infection in most cases is from infected lower
molars or from pericoronitis, which is an infection of the gums surrounding the
partially erupted lower (usually third) molars. Although the widespread
involvement seen in Ludwig's usually develops in immunocompromised persons, it
can also develop in otherwise healthy individuals. Ludwig's angina is a fascial
space infection with bilateral involvement of the submandibular, sublingual and
submental spaces. The external signs may include bilateral lower facial edema
around the mandible and upper neck. Intraoral signs may include a raised floor
of mouth due to sublingual space involvement and posterior displacement of the
tongue. Symptoms may include dysphagia, odynophagia, difficulty breathing, and
pain.
* Lung abscess is a type of liquefactive necrosis of the lung tissue and
formation of cavities (more than 2 cm) containing necrotic debris or fluid
caused by microbial infection. This pus-filled cavity is often caused by
aspiration, which may occur during anesthesia, sedation, or unconsciousness from
injury. Alcoholism is the most common condition predisposing to lung abscesses.
Onset of symptoms is often gradual, but in necrotizing staphylococcal or
gram-negative bacillary pneumonias patients can be acutely ill. Cough, fever
with shivering, and night sweats are often present. Cough can be productive of
foul smelling purulent mucus (≈70%) or less frequently with blood in one third
of cases). Affected individuals may also complain of chest pain, shortness of
breath, lethargy and other features of chronic illness. Those with a lung
abscess are generally cachectic at presentation. Finger clubbing is present in
one third of patients. Dental decay is common especially in alcoholics and
children. On examination of the chest there will be features of consolidation
such as localized dullness on percussion and bronchial breath sounds. Conditions
contributing to lung abscess: Aspiration of oropharyngeal or gastric secretion.
Septic emboli. Necrotizing pneumonia. Vasculitis: Granulomatosis with
polyangiitis. Necrotizing tumors: 8% to 18% are due to neoplasms across all age
groups, higher in older people; primary squamous carcinoma of the lung is the
most common. Anaerobic bacteria: Actinomyces, Peptostreptococcus, Bacteroides,
Fusobacterium species. Microaerophilic streptococcus : Streptococcus milleri.
Aerobic bacteria: Staphylococcus, Klebsiella, Haemophilus, Pseudomonas,
Nocardia, Escherichia coli, Streptococcus, Mycobacteria. Fungi: Candida,
Aspergillus. Parasites: Entamoeba histolytica.
* Lung collapse or atelectasis is the collapse or closure of a lung resulting in
reduced or absent gas exchange. It may affect part or all of a lung. It is
usually not bilateral. It is a condition where the alveoli are deflated down to
little or no volume, as distinct from pulmonary consolidation, in which they are
filled with liquid. It is often called a collapsed lung, although that term may
also refer to pneumothorax. Although frequently described as a collapse of lung
tissue, atelectasis is not synonymous with a pneumothorax, which is a more
specific condition that features atelectasis. Acute atelectasis may occur as a
post-operative complication or as a result of surfactant deficiency. In
premature neonates, this leads to infant respiratory distress syndrome. May have
no signs and symptoms or they may include: cough, but not prominent; chest pain
(not common); breathing difficulty (fast and shallow); low oxygen saturation;
pleural effusion (transudate type); cyanosis (late sign); increased heart rate.
The most common cause is post-surgical atelectasis, characterized by splinting,
i.e. restricted breathing after abdominal surgery. Other most common cause is
pulmonary Koch. Smokers and the elderly are at an increased risk. Outside of
this context, atelectasis implies some blockage of a bronchiole or bronchus,
which can be within the airway (foreign body, mucus plug), from the wall (tumor,
usually squamous cell carcinoma) or compressing from the outside (tumor, lymph
node, tubercle). Another cause is poor surfactant spreading during inspiration,
causing the surface tension to be at its highest which tends to collapse smaller
alveoli. Atelectasis may also occur during suction, as along with sputum, air is
withdrawn from the lungs.
* Lung interstitial diseases, large group of diseases that inflame or scar the
lungs. The inflammation and scarring make it hard to get enough oxygen.
* Lymphadenitis, inflammation of a lymph node.
* Lymphangiomas are malformations of the lymphatic system characterized by
lesions that are thin-walled cysts; these cysts can be macroscopic, as in a
cystic hygroma, or microscopic. The lymphatic system is the network of vessels
responsible for returning to the venous system excess fluid from tissues as well
as the lymph nodes that filter this fluid for signs of pathogens. These
malformations can occur at any age and may involve any part of the body, but 90%
occur in children less than 2 years of age and involve the head and neck. These
malformations are either congenital or acquired. Most lymphangiomas are benign
lesions that result only in a soft, slow-growing, "doughy" mass. Since they have
no chance of becoming malignant, lymphangiomas are usually treated for cosmetic
reasons only. Rarely, impingement upon critical organs may result in
complications, such as respiratory distress when a lymphangioma compresses the
airway. There are three distinct types of lymphangioma, each with their own
symptoms. They are distinguished by the depth and the size of abnormal lymph
vessels, but all involve a malformation of the lymphic system. Lymphangioma
circumscriptum can be found on the skin's surface, and the other two types of
lymphangiomas occur deeper under the skin.
* Lymphedema is a condition of localized fluid retention and tissue swelling
caused by a compromised lymphatic system, which normally returns interstitial
fluid to the thoracic duct, then the bloodstream. The condition can be inherited
or can be caused by a birth defect, though it is frequently caused by cancer
treatments and by parasitic infections. Symptoms may include a feeling of
heaviness or fullness, edema, and (occasionally) aching pain in the affected
area. In advanced lymphedema, there may be the presence of skin changes such as
discoloration, verrucous (wart-like) hyperplasia, hyperkeratosis and
papillomatosis; and eventually deformity (elephantiasis). Lymphedema should not
be confused with edema arising from venous insufficiency, which is not
lymphedema. However, untreated venous insufficiency can progress into a combined
venous/lymphatic disorder which is treated the same way as lymphedema.
Lymphedema affects approximately 140 million people worldwide. Lymphedema may be
inherited (primary) or caused by injury to the lymphatic vessels (secondary). It
is most frequently seen after lymph node dissection, surgery and/or radiation
therapy, in which damage to the lymphatic system is caused during the treatment
of cancer, most notably breast cancer. In many patients with cancer, this
condition does not develop until months or even years after therapy has
concluded. Lymphedema may also be associated with accidents or certain diseases
or problems that may inhibit the lymphatic system from functioning properly. In
tropical areas of the world, a common cause of secondary lymphedema is
filariasis, a parasitic infection. It can also be caused by a compromising of
the lymphatic system resulting from cellulitis.
* Lymphogranuloma venereum (LGV) is an uncommon sexually transmitted disease
(STD) caused by Chlamydia trachomatis. LGV is endemic in certain areas of
Africa, Southeast Asia, India, the Caribbean, and South America. It is rare in
industrialized countries, but in the last 10 years has been increasingly
recognized in North America, Europe, and the United Kingdom as causing outbreaks
of proctitis among men who have sex with men (MSM). LGV is a subtype of genital
ulcer diseases that include other STDs, such as HSV-2, syphilis, and chancroid.
This condition is characterized by self-limited genital papules or ulcers
followed by painful inguinal and/or femoral lymphadenopathy, which may be the
only clinical manifestation at presentation. Patients with LGV may also present
with rectal ulcerations and symptoms of proctocolitis, especially among patients
participating in receptive anal intercourse. In these cases, rectal pain,
discharge, and bleeding may be confused with other GI conditions such as
colitis. If left untreated, disfiguring ulceration and enlargement of the
external genitalia, and subsequent lymphatic obstruction, may occur.
* Lymphoproliferative disorders (LPDs) refer to several conditions in which
lymphocytes are produced in excessive quantities. They typically occur in people
who have a compromised immune system. They are sometimes equated with
"immunoproliferative disorders", but technically lymphoproliferative disorders
are a subset of immunoproliferative disorders, along with hypergammaglobulinemia
and paraproteinemias. Lymphoproliferative disorders are a set of disorders
characterized by the abnormal proliferation of lymphocytes into a monoclonal
lymphocytosis. The two major types of lymphocytes are B cells and T cells, which
are derived from pluripotent hematopoetic stem cells in the bone marrow.
Individuals who have some sort of dysfunction with their immune system are
susceptible to develop a lymphoproliferative disorder because when any of the
numerous control points of the immune system become dysfunctional,
immunodeficiency or deregulation of lymphocytes is more likely to occur. Lymph
nodes are distributed throughout the body to fight against infection. The
spleen, located in the left upper section of the abdomen, stores blood and also
protects the body against infection. In those with a lymphoproliferative
disorder, increased lymphocytes in the bloodstream can lead to the enlargement
of the lymph nodes and the spleen. Many of these disorders originate from
inherited conditions and sometimes are caused by acquired immune system
dysfunction. Other cases, however, have no known cause.
* Lysosomal storage diseases, produce an abnormal accumulation of a protein,
lipid, pigment, or other compound in the body.